https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Th22 cells form a distinct Th lineage from Th17 cells in vitro with unique transcriptional properties and Tbet-dependent Th1 plasticity https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:33753 Wed 13 Feb 2019 09:58:18 AEDT ]]> IL-22 and its receptors are increased in human and experimental COPD and contribute to pathogenesis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:46962 Il22−/−) mice. CS-induced airway remodelling and emphysema-like alveolar enlargement did not occur in Il22−/− mice. Il22−/− mice had improved lung function in terms of airway resistance, total lung capacity, inspiratory capacity, forced vital capacity and compliance. These data highlight important roles for IL-22 and its receptors in human COPD and CS-induced experimental COPD.]]> Mon 12 Dec 2022 14:27:30 AEDT ]]>